Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate

Nonsense-mediated RNA decay (NMD) is a highly conserved pathway that selectively degrades specific subsets of RNA transcripts. Here, we provide evidence that NMD regulates early human developmental cell fate. We found that NMD factors tend to be expressed at higher levels in human pluripotent cells...

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Detalles Bibliográficos
Autores principales: Lou, Chih-Hong, Dumdie, Jennifer, Goetz, Alexandra, Shum, Eleen Y., Brafman, David, Liao, Xiaoyan, Mora-Castilla, Sergio, Ramaiah, Madhuvanthi, Cook-Andersen, Heidi, Laurent, Louise, Wilkinson, Miles F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912386/
https://www.ncbi.nlm.nih.gov/pubmed/27304915
http://dx.doi.org/10.1016/j.stemcr.2016.05.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912386/
https://www.ncbi.nlm.nih.gov/pubmed/27304915
http://dx.doi.org/10.1016/j.stemcr.2016.05.008

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