Zebrafish behavioral profiling identifies multi-target antipsychotic-like compounds

Many psychiatric drugs act on multiple targets and therefore require screening assays that encompass a wide target space. With sufficiently rich phenotyping, and a large sampling of compounds, it should be possible to identify compounds with desired mechanisms of action based on their behavioral pro...

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Detalles Bibliográficos
Autores principales: Bruni, Giancarlo, Rennekamp, Andrew J., Velenich, Andrea, McCarroll, Matthew, Gendelev, Leo, Fertsch, Ethan, Taylor, Jack, Lakhani, Parth, Lensen, Dennis, Evron, Tama, Lorello, Paul J., Huang, Xi-Ping, Kolczewski, Sabine, Carey, Galen, Caldarone, Barbara J., Prinssen, Eric, Roth, Bryan L., Keiser, Michael J., Peterson, Randall T., Kokel, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912417/
https://www.ncbi.nlm.nih.gov/pubmed/27239787
http://dx.doi.org/10.1038/nchembio.2097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912417/
https://www.ncbi.nlm.nih.gov/pubmed/27239787
http://dx.doi.org/10.1038/nchembio.2097

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