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Interleukin-21 plays a critical role in the pathogenesis and severity of type I autoimmune hepatitis
BACKGROUND AND AIMS: Recently, the number of follicular helper T (Tfh) cells expressing interleukin (IL)-21 was found to increase in peripheral blood of human and murine models of autoimmune hepatitis (AIH). IL-21, the most recently discovered member of the type-I cytokine family, exerts various eff...
Autores principales: | Abe, Kazumichi, Takahashi, Atsushi, Imaizumi, Hiromichi, Hayashi, Manabu, Okai, Ken, Kanno, Yukiko, Watanabe, Hiroshi, Ohira, Hiromasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912506/ https://www.ncbi.nlm.nih.gov/pubmed/27386263 http://dx.doi.org/10.1186/s40064-016-2512-y |
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