Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines

Dozens of transgenic mouse models, generally based on mutations associated with familial Alzheimer's disease (AD), have been developed, in part, for preclinical testing of candidate AD therapies. However, none of these models has successfully predicted the clinical efficacy of drugs for treatin...

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Detalles Bibliográficos
Autores principales: Keene, C. Dirk, Darvas, Martin, Kraemer, Brian, Liggitt, Denny, Sigurdson, Christina, Ladiges, Warren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2016
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912600/
https://www.ncbi.nlm.nih.gov/pubmed/27317189
http://dx.doi.org/10.3402/pba.v6.32397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912600/
https://www.ncbi.nlm.nih.gov/pubmed/27317189
http://dx.doi.org/10.3402/pba.v6.32397

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