A broad analysis of resistance development in the malaria parasite

Microbial resistance to chemotherapy has caused countless deaths where malaria is endemic. Chemotherapy may fail either due to pre-existing resistance or evolution of drug-resistant parasites. Here we use a diverse set of antimalarial compounds to investigate the acquisition of drug resistance and t...

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Detalles Bibliográficos
Autores principales: Corey, Victoria C., Lukens, Amanda K., Istvan, Eva S., Lee, Marcus C. S., Franco, Virginia, Magistrado, Pamela, Coburn-Flynn, Olivia, Sakata-Kato, Tomoyo, Fuchs, Olivia, Gnädig, Nina F., Goldgof, Greg, Linares, Maria, Gomez-Lorenzo, Maria G., De Cózar, Cristina, Lafuente-Monasterio, Maria Jose, Prats, Sara, Meister, Stephan, Tanaseichuk, Olga, Wree, Melanie, Zhou, Yingyao, Willis, Paul A., Gamo, Francisco-Javier, Goldberg, Daniel E., Fidock, David A., Wirth, Dyann F., Winzeler, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912613/
https://www.ncbi.nlm.nih.gov/pubmed/27301419
http://dx.doi.org/10.1038/ncomms11901

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