A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC

Colorectal cancer (CRC) is a highly heterogeneous disease, for which prognosis has been relegated to clinicopathologic staging for decades. There is a need to stratify subpopulations of CRC on a molecular basis to better predict outcome and assign therapies. Here we report targeted exome-sequencing...

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Detalles Bibliográficos
Autores principales: Schell, Michael J., Yang, Mingli, Teer, Jamie K., Lo, Fang Yin, Madan, Anup, Coppola, Domenico, Monteiro, Alvaro N. A., Nebozhyn, Michael V., Yue, Binglin, Loboda, Andrey, Bien-Willner, Gabriel A., Greenawalt, Danielle M., Yeatman, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912618/
https://www.ncbi.nlm.nih.gov/pubmed/27302369
http://dx.doi.org/10.1038/ncomms11743

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