A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity

Stem cell identity depends on the integration of extrinsic and intrinsic signals, which directly influence the maintenance of their epigenetic state. Although Myc transcription factors play a major role in stem cell self-renewal and pluripotency, their integration with signalling pathways and epigen...

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Detalles Bibliográficos
Autores principales: Fagnocchi, Luca, Cherubini, Alessandro, Hatsuda, Hiroshi, Fasciani, Alessandra, Mazzoleni, Stefania, Poli, Vittoria, Berno, Valeria, Rossi, Riccardo L., Reinbold, Rolland, Endele, Max, Schroeder, Timm, Rocchigiani, Marina, Szkarłat, Żaneta, Oliviero, Salvatore, Dalton, Stephen, Zippo, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912626/
https://www.ncbi.nlm.nih.gov/pubmed/27301576
http://dx.doi.org/10.1038/ncomms11903

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