Cargando…

Macrophage Immune Response Suppression by Recombinant Mycobacterium tuberculosis Antigens, the ESAT-6, CFP-10, and ESAT-6/CFP-10 Fusion Proteins

BACKGROUND: Macrophage immune responses are affected by the secretory proteins of Mycobacterium tuberculosis (Mtb). This study aimed to examine the immune responses of macrophages to Mtb secretory antigens, namely ESAT-6, CFP-10, and ESAT-6/CFP-10. METHODS: THP-1 cells (a human monocytic cell line)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seghatoleslam, Atefeh, Hemmati, Mina, Ebadat, Saeedeh, Movahedi, Bahram, Mostafavi-Pour, Zohreh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Iranian Journal of Medical Sciences 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912648/ https://www.ncbi.nlm.nih.gov/pubmed/27365551

Ejemplares similares

Expression and Purification of Recombinant Mycobacterium Tuberculosis (TB) Antigens, ESAT-6, CFP-10 and ESAT- 6/CFP-10 and Their Diagnosis Potential for Detection of TB Patients
por: Hemmati, M, et al.
Publicado: (2011)

IFN-γ and IL-2 Responses to Recombinant AlaDH against ESAT-6/CFP-10 Fusion Antigens in the Diagnosis of Latent versus Active Tuberculosis Infection
por: Movahedi, Bahram, et al.
Publicado: (2017)

Oral Immunogenicity of Plant-Made Mycobacterium tuberculosis ESAT6 and CFP10
por: Uvarova, Elena A., et al.
Publicado: (2013)

Cloning, expression and purification of Mycobacterium tuberculosis ESAT-6 and CFP-10 antigens
por: Mahmoudi, Shima, et al.
Publicado: (2013)

Cytotoxic Effect of Recombinant Mycobacterium tuberculosis CFP-10/ESAT-6 Protein on the Crucial Pathways of WI-38 Cells
por: Tsai, Kun-Nan, et al.
Publicado: (2009)

Mycobacterium Tuberculosis Infection in Rhesus Monkeys (Macaca mulatta) and Evaluation of ESAT-6 and CFP10 as Immunodiagnostic Antigens(#)
por: Min, Fangui, et al.
Publicado: (2013)

A Novel B-Cell Epitope Identified within Mycobacterium tuberculosis CFP10/ESAT-6 Protein
por: Yang, Hua, et al.
Publicado: (2013)

Aptasensor for the Detection of Mycobacterium tuberculosis in Sputum Utilising CFP10-ESAT6 Protein as a Selective Biomarker
por: Azmi, Umi Zulaikha Mohd, et al.
Publicado: (2021)

Effects of Mycobacterium tuberculosis ESAT6-CFP10 Protein on Cell Viability and Production of Nitric Oxide in Alveolar Macrophages
por: Xie, Xiaoli, et al.
Publicado: (2016)

Evaluation of ESAT6-CFP10 Skin Test for Mycobacterium tuberculosis Infection among Persons Living with HIV in China
por: Lu, Peng, et al.
Publicado: (2023)

ESAT-6/CFP10 Skin Test Predicts Disease in M. tuberculosis-Infected Guinea Pigs
por: Weldingh, Karin, et al.
Publicado: (2008)

Factors associated with differential T cell responses to antigens ESAT-6 and CFP-10 in pulmonary tuberculosis patients
por: Liu, Shengsheng, et al.
Publicado: (2021)

Evaluating the Performance of PPE44, HSPX, ESAT-6 and CFP-10 Factors in Tuberculosis Subunit Vaccines
por: Valizadeh, Azar, et al.
Publicado: (2022)

In Vitro and In Vivo Antigen Presentation and Diagnosis Development of Recombinant Overlapping Peptides Corresponding to Mtb ESAT-6/CFP-10
por: Zhang, Qing, et al.
Publicado: (2022)

Utility of recombinant fusion protein ESAT6-CFP10 skin test for differential diagnosis of active tuberculosis: A prospective study
por: Yuan, Yuan, et al.
Publicado: (2023)

Development of Gold-Nanoparticle-Based Lateral Flow Immunoassays for Rapid Detection of TB ESAT-6 and CFP-10
por: Seele, Palesa Pamela, et al.
Publicado: (2023)

Characteristic profile of antibody responses to PPD, ESAT-6, and CFP-10 of Mycobacterium tuberculosis in pulmonary tuberculosis suspected cases in Surabaya, Indonesia
por: Dewi, Desak Nyoman Surya Suameitria, et al.
Publicado: (2019)

Serodiagnostic Efficacy of Mycobacterium tuberculosis 30/32-kDa Mycolyl Transferase Complex, ESAT-6, and CFP-10 in Patients with Active Tuberculosis
por: Kumar, Gavish, et al.
Publicado: (2010)

Comparison of the Performance of Urinary Mycobacterium tuberculosis Antigens Cocktail (ESAT6, CFP10, and MPT64) with Culture and Microscopy in Pulmonary Tuberculosis Patients
por: Turbawaty, Dewi Kartika, et al.
Publicado: (2017)

Preparation of immunochromatographic strips for rapid detection of early secreted protein ESAT-6 and culture filtrate protein CFP-10 from Mycobacterium tuberculosis
por: Wu, Xiaoxin, et al.
Publicado: (2017)

Signal Regulatory Protein α (SIRPα)(+) Cells in the Adaptive Response to ESAT-6/CFP-10 Protein of Tuberculous Mycobacteria
por: Waters, W. Ray, et al.
Publicado: (2009)

Immune Responses to ESAT-6 and CFP-10 by FASCIA and Multiplex Technology for Diagnosis of M. tuberculosis Infection; IP-10 Is a Promising Marker
por: Borgström, Emilie, et al.
Publicado: (2012)

Recombinant ESAT-6-CFP10 Fusion Protein Induction of Th1/Th2 Cytokines and FoxP3 Expressing Treg Cells in Pulmonary TB
por: Jackson-Sillah, Dolly, et al.
Publicado: (2013)

Induration or erythema diameter not less than 5 mm as results of recombinant fusion protein ESAT6-CFP10 skin test for detecting M. tuberculosis infection
por: Zhang, Hui, et al.
Publicado: (2020)

First-in-Man Open Clinical Trial of a Combined rdESAT-6 and rCFP-10 Tuberculosis Specific Skin Test Reagent
por: Bergstedt, Winnie, et al.
Publicado: (2010)

Changes in cytokine responses to TB antigens ESAT-6, CFP-10 and TB 7.7 and inflammatory markers in peripheral blood during therapy
por: Leem, Ah Young, et al.
Publicado: (2018)

Surface Enhanced CdSe/ZnS QD/SiNP Electrochemical Immunosensor for the Detection of Mycobacterium Tuberculosis by Combination of CFP10-ESAT6 for Better Diagnostic Specificity
por: Mohd Bakhori, Noremylia, et al.
Publicado: (2019)

Differences in plasma proteomes for active tuberculosis, latent tuberculosis and non-tuberculosis mycobacterial lung disease patients with and without ESAT-6/CFP10 stimulation
por: Teklu, Takele, et al.
Publicado: (2020)

Safety of a Novel ESAT6-CFP10 skin test compared with tuberculin skin test in a double-blind, randomized, controlled study
por: Yang, Yang, et al.
Publicado: (2022)

Detection of natural infection with Mycobacterium intracellulare in healthy wild-caught Chacma baboons (Papio ursinus) by ESAT-6 and CFP-10 IFN-γ ELISPOT tests following a tuberculosis outbreak
por: Chege, Gerald K, et al.
Publicado: (2008)

Comparative sensitivity of the test with tuberculosis recombinant allergen, containing ESAT6-CFP10 protein, and Mantoux test with 2 TU PPD-L in newly diagnosed tuberculosis children and adolescents in Moscow
por: Slogotskaya, Liudmila, et al.
Publicado: (2018)

A peptide fragment from the human COX3 protein disrupts association of Mycobacterium tuberculosis virulence proteins ESAT-6 and CFP10, inhibits mycobacterial growth and mounts protective immune response
por: Samuchiwal, Sachin Kumar, et al.
Publicado: (2014)

Phosphorylation of CFP10 modulates Mycobacterium tuberculosis virulence
por: Malakar, Basanti, et al.
Publicado: (2023)

High Positivity Rate of Urinary Mycobacterium tuberculosis Antigens Cocktail (ESAT-6, CFP-10, and MPT-64) in Active Tuberculosis Patients With and Without Human Immunodeficiency Virus Infection: A Cross-Sectional Study
por: Turbawaty, Dewi Kartika, et al.
Publicado: (2023)

Association of ESAT‐6/CFP‐10‐induced IFN‐γ, TNF‐α and IL‐10 with clinical tuberculosis: evidence from cohorts of pulmonary tuberculosis patients, household contacts and community controls in an endemic setting
por: Abebe, F., et al.
Publicado: (2017)

Sensitivity, Specificity, and Safety of a Novel ESAT6-CFP10 Skin Test for Tuberculosis Infection in China: 2 Randomized, Self-Controlled, Parallel-Group Phase 2b Trials
por: Xu, Miao, et al.
Publicado: (2021)

A Toolbox for Tuberculosis (TB) Diagnosis: An Indian Multi-Centric Study (2006-2008); Evaluation of Serological Assays Based on PGL-Tb1 and ESAT-6/CFP10 Antigens for TB Diagnosis
por: Lagrange, Philippe H., et al.
Publicado: (2014)

Introducing the ESAT-6 free IGRA, a companion diagnostic for TB vaccines based on ESAT-6
por: Ruhwald, Morten, et al.
Publicado: (2017)

Transcriptional analysis of ESAT-6 cluster 3 in Mycobacterium smegmatis
por: Maciąg, Anna, et al.
Publicado: (2009)

Development of ESAT-6 Based Immunosensor for the Detection of Mycobacterium tuberculosis
por: Omar, Rishabh Anand, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0aadnea69icdd8m1s1l86ronim