Intrathecal administration of TRPA1 antagonists attenuate cyclophosphamide-induced cystitis in rats with hyper-reflexia micturition

BACKGROUND: The activation of TRPA1 channel is implicated in hyper-reflexic micturition similar to overactive bladder. In this study, we aimed to investigate the effects of blocking TRPA1 via intrathecal administration of antagonists on the afferent pathways of micturition in rats with cystitis. MET...

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Detalles Bibliográficos
Autores principales: Chen, Zhipeng, Du, Shuqi, Kong, Chuize, Zhang, Zhe, Mokhtar, Al-dhabi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912737/
https://www.ncbi.nlm.nih.gov/pubmed/27315798
http://dx.doi.org/10.1186/s12894-016-0150-x

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