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Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice

BACKGROUND: Endothelial dysfunction has been suggested as a possible causal link between hyperglycemia and microvascular complications in diabetes mellitus. The effect of metformin on endothelial progenitor cells (EPCs) is still unclear. This study was designed to test the hypothesis that metformin...

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Detalles Bibliográficos
Autores principales:	Yu, Jia-Wen, Deng, Ya-Ping, Han, Xue, Ren, Guo-Fei, Cai, Jian, Jiang, Guo-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912824/ https://www.ncbi.nlm.nih.gov/pubmed/27316923 http://dx.doi.org/10.1186/s12933-016-0408-3

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