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The Relation between Hepatotoxicity and the Total Coumarin Intake from Traditional Japanese Medicines Containing Cinnamon Bark

Cinnamon bark is commonly used in traditional Japanese herbal medicines (Kampo medicines). The coumarin contained in cinnamon is known to be hepatotoxic, and a tolerable daily intake (TDI) of 0.1 mg/kg/day, has been quantified and used in Europe to insure safety. Risk assessments for hepatotoxicity...

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Detalles Bibliográficos
Autores principales:	Iwata, Naohiro, Kainuma, Mosaburo, Kobayashi, Daisuke, Kubota, Toshio, Sugawara, Naoko, Uchida, Aiko, Ozono, Sahoko, Yamamuro, Yuki, Furusyo, Norihiro, Ueda, Koso, Tahara, Eiichi, Shimazoe, Takao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913087/ https://www.ncbi.nlm.nih.gov/pubmed/27378929 http://dx.doi.org/10.3389/fphar.2016.00174

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