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Long-term study of the impact of methotrexate on serum cytokines and lymphocyte subsets in patients with active rheumatoid arthritis: correlation with pharmacokinetic measures

OBJECTIVE: To describe changes in immune parameters observed during long-term methotrexate (MTX) therapy in patients with active rheumatoid arthritis (RA) and explore correlations with simultaneously measured MTX pharmacokinetic (PKC) parameters. DESIGN: Prospective, open-label, long-term mechanism...

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Detalles Bibliográficos
Autores principales:	Kremer, Joel M, Lawrence, David A, Hamilton, Robert, McInnes, Iain B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Rheumatoid Arthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913203/ https://www.ncbi.nlm.nih.gov/pubmed/27335660 http://dx.doi.org/10.1136/rmdopen-2016-000287

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