Fibroblasts profiling in scarring trachoma identifies IL-6 as a functional component of a fibroblast-macrophage pro-fibrotic and pro-inflammatory feedback loop

Trachoma is a conjunctiva scarring disease, which is the leading infectious cause of blindness worldwide. Yet, the molecular mechanisms underlying progressive fibrosis in trachoma are unknown. To investigate the contribution of local resident fibroblasts to disease progression, we isolated conjuncti...

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Detalles Bibliográficos
Autores principales: Kechagia, Jenny Z., Ezra, Daniel G., Burton, Matthew J., Bailly, Maryse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913315/
https://www.ncbi.nlm.nih.gov/pubmed/27321784
http://dx.doi.org/10.1038/srep28261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913315/
https://www.ncbi.nlm.nih.gov/pubmed/27321784
http://dx.doi.org/10.1038/srep28261

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