Cargando…

Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway inflammation

BACKGROUND: Exosomes are nano-sized extracellular vesicles participating in cell-to-cell communication both in health and disease. However, the knowledge about the functions and molecular composition of exosomes in the upper airways is limited. The aim of the current study was therefore to determine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lässer, Cecilia, O’Neil, Serena E., Shelke, Ganesh V., Sihlbom, Carina, Hansson, Sara F., Gho, Yong Song, Lundbäck, Bo, Lötvall, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913423/ https://www.ncbi.nlm.nih.gov/pubmed/27320496 http://dx.doi.org/10.1186/s12967-016-0927-4

Ejemplares similares

Importance of exosome depletion protocols to eliminate functional and RNA-containing extracellular vesicles from fetal bovine serum
por: Shelke, Ganesh Vilas, et al.
Publicado: (2014)

Extracellular vesicles from mast cells induce mesenchymal transition in airway epithelial cells
por: Yin, Yanan, et al.
Publicado: (2020)

Endosomal signalling via exosome surface TGFβ-1
por: Shelke, Ganesh Vilas, et al.
Publicado: (2019)

DNA analysis of low- and high-density fractions defines heterogeneous subpopulations of small extracellular vesicles based on their DNA cargo and topology
por: Lázaro-Ibáñez, Elisa, et al.
Publicado: (2019)

Mast cell exosomes promote lung adenocarcinoma cell proliferation – role of KIT-stem cell factor signaling
por: Xiao, Hui, et al.
Publicado: (2014)

Isolation and Characterization of RNA-Containing Exosomes
por: Lässer, Cecilia, et al.
Publicado: (2012)

T2 and T17 cytokines alter the cargo and function of airway epithelium-derived extracellular vesicles
por: Ax, Elisabeth, et al.
Publicado: (2020)

Immune-Associated Proteins Are Enriched in Lung Tissue-Derived Extracellular Vesicles during Allergen-Induced Eosinophilic Airway Inflammation
por: Lässer, Cecilia, et al.
Publicado: (2021)

Enhancement of therapeutic potential of mesenchymal stem cell-derived extracellular vesicles
por: Park, Kyong-Su, et al.
Publicado: (2019)

Detailed Analysis of Protein Topology of Extracellular Vesicles–Evidence of Unconventional Membrane Protein Orientation
por: Cvjetkovic, Aleksander, et al.
Publicado: (2016)

Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing
por: Lässer, Cecilia, et al.
Publicado: (2016)

MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal melanoma
por: Eldh, Maria, et al.
Publicado: (2014)

Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells – Evidence of unique microRNA cargos
por: Lunavat, Taral R, et al.
Publicado: (2015)

Circulating eosinophil progenitors express major trafficking related molecules and are more activated compared to mature eosinophils in patients with asthma
por: Lu, You, et al.
Publicado: (2013)

Exosomes purified from a single cell type have diverse morphology
por: Zabeo, Davide, et al.
Publicado: (2017)

Network analysis of quantitative proteomics on asthmatic bronchi: effects of inhaled glucocorticoid treatment
por: O'Neil, Serena E, et al.
Publicado: (2011)

Mesenchymal stromal cell-derived nanovesicles ameliorate bacterial outer membrane vesicle-induced sepsis via IL-10
por: Park, Kyong-Su, et al.
Publicado: (2019)

The International Society for Extracellular Vesicles launches the first massive open online course on extracellular vesicles
por: Lässer, Cecilia, et al.
Publicado: (2016)

Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes
por: Crescitelli, Rossella, et al.
Publicado: (2013)

Membrane trafficking: vesicle formation, cargo sorting and fusion
por: Miaczynska, Marta, et al.
Publicado: (2020)

Regulation of exosome production and cargo sorting
por: Wei, Hong, et al.
Publicado: (2021)

Escherichia coli outer membrane vesicles can contribute to sepsis induced cardiac dysfunction
por: Svennerholm, Kristina, et al.
Publicado: (2017)

Respiratory Syncytial Virus Infection Changes Cargo Composition of Exosome Released from Airway Epithelial Cells
por: Chahar, Harendra Singh, et al.
Publicado: (2018)

Epithelial IL-33 appropriates exosome trafficking for secretion in chronic airway disease
por: Katz-Kiriakos, Ella, et al.
Publicado: (2021)

The influence of rotor type and centrifugation time on the yield and purity of extracellular vesicles
por: Cvjetkovic, Aleksander, et al.
Publicado: (2014)

Optineurin: A Coordinator of Membrane-Associated Cargo Trafficking and Autophagy
por: Ryan, Thomas A., et al.
Publicado: (2018)

Surf4, cargo trafficking, lipid metabolism, and therapeutic implications
por: Shen, Yishi, et al.
Publicado: (2022)

Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages
por: Lässer, Cecilia, et al.
Publicado: (2011)

Staphylococcal trafficking and infection—from ‘nose to gut’ and back
por: Raineri, Elisa J M, et al.
Publicado: (2021)

Endocytic Trafficking of Membrane-Bound Cargo: A Flotillin Point of View
por: Meister, Melanie, et al.
Publicado: (2014)

Epidermal T Cell Dendrites Serve as Conduits for Bidirectional Trafficking of Granular Cargo
por: Chodaczek, Grzegorz, et al.
Publicado: (2018)

NPC1 plays a role in the trafficking of specific cargo to melanosomes
por: Rus, Alina Adriana, et al.
Publicado: (2023)

Quantitative expression of osteopontin in nasal mucosa of patients with allergic rhinitis: effects of pollen exposure and nasal glucocorticoid treatment
por: O'Neil, Serena E, et al.
Publicado: (2010)

Inhibition of endolysosome fusion increases exosome secretion
por: Shelke, Ganesh Vilas, et al.
Publicado: (2023)

Cortactin enhances exosome secretion without altering cargo
por: Gangoda, Lahiru, et al.
Publicado: (2016)

Exosomal cargoes in OSCC: current findings and potential functions
por: Zhao, Chengzhi, et al.
Publicado: (2020)

Alarming Cargo: The Role of Exosomes in Trauma-Induced Inflammation
por: Walsh, Sarah A., et al.
Publicado: (2021)

Exosomal Protease Cargo as Prognostic Biomarker in Colorectal Cancer
por: Yunusova, Natalia V., et al.
Publicado: (2021)

Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment
por: Tan, Shiming, et al.
Publicado: (2023)

Current Strategies for Exosome Cargo Loading and Targeting Delivery
por: Zeng, Haifeng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sdqcvtrck1e0d0m5j4v052qr38