Cargando…

Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis

Almost 20 years has passed since trichomonosis was first recognized as a potential cause of diarrhea in domestic cats. Despite progress in confirming disease causation, developing means for diagnosis, and identifying approaches to treatment of the infection, we still know very little about how this...

Descripción completa

Detalles Bibliográficos
Autores principales: Tolbert, M.K., Gookin, J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913604/
https://www.ncbi.nlm.nih.gov/pubmed/26946069
http://dx.doi.org/10.1111/jvim.13920
_version_ 1782438428216918016
author Tolbert, M.K.
Gookin, J.L.
author_facet Tolbert, M.K.
Gookin, J.L.
author_sort Tolbert, M.K.
collection PubMed
description Almost 20 years has passed since trichomonosis was first recognized as a potential cause of diarrhea in domestic cats. Despite progress in confirming disease causation, developing means for diagnosis, and identifying approaches to treatment of the infection, we still know very little about how this parasite causes diarrhea. With increasing recognition of resistance of trichomonosis to treatment with 5‐nitroimidazole drugs, new treatment strategies based on an understanding of disease pathogenesis are needed. In this review, lessons learned from the pathogenesis of venereal trichomonosis in people and cattle are applied to clinical observations of trichomonosis in cats in effort to generate insight into areas where further research may be beneficial.
format Online
Article
Text
id pubmed-4913604
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-49136042016-06-22 Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis Tolbert, M.K. Gookin, J.L. J Vet Intern Med SMALL ANIMAL Almost 20 years has passed since trichomonosis was first recognized as a potential cause of diarrhea in domestic cats. Despite progress in confirming disease causation, developing means for diagnosis, and identifying approaches to treatment of the infection, we still know very little about how this parasite causes diarrhea. With increasing recognition of resistance of trichomonosis to treatment with 5‐nitroimidazole drugs, new treatment strategies based on an understanding of disease pathogenesis are needed. In this review, lessons learned from the pathogenesis of venereal trichomonosis in people and cattle are applied to clinical observations of trichomonosis in cats in effort to generate insight into areas where further research may be beneficial. John Wiley and Sons Inc. 2016-03-04 2016 /pmc/articles/PMC4913604/ /pubmed/26946069 http://dx.doi.org/10.1111/jvim.13920 Text en Copyright © 2016 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle SMALL ANIMAL
Tolbert, M.K.
Gookin, J.L.
Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis
title Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis
title_full Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis
title_fullStr Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis
title_full_unstemmed Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis
title_short Mechanisms of Tritrichomonas foetus Pathogenicity in Cats with Insights from Venereal Trichomonosis
title_sort mechanisms of tritrichomonas foetus pathogenicity in cats with insights from venereal trichomonosis
topic SMALL ANIMAL
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913604/
https://www.ncbi.nlm.nih.gov/pubmed/26946069
http://dx.doi.org/10.1111/jvim.13920
work_keys_str_mv AT tolbertmk mechanismsoftritrichomonasfoetuspathogenicityincatswithinsightsfromvenerealtrichomonosis
AT gookinjl mechanismsoftritrichomonasfoetuspathogenicityincatswithinsightsfromvenerealtrichomonosis