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Non‐glycosidic compounds can stimulate both human and mouse iNKT cells

Invariant natural killer T (iNKT) cells recognize CD1d/glycolipid complexes and upon activation with synthetic agonists display immunostimulatory properties. We have previously described that the non‐glycosidic CD1d‐binding lipid, threitolceramide (ThrCer) activates murine and human iNKT cells. Here...

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Detalles Bibliográficos
Autores principales:	Jukes, John‐Paul, Gileadi, Uzi, Ghadbane, Hemza, Yu, Ting‐Fong, Shepherd, Dawn, Cox, Liam R., Besra, Gurdyal S., Cerundolo, Vincenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Immunomodulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913735/ https://www.ncbi.nlm.nih.gov/pubmed/26873393 http://dx.doi.org/10.1002/eji.201546114

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