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Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells
Disassembly of the cone-shaped HIV-1 capsid in target cells is a prerequisite for establishing a life-long infection. This step in HIV-1 entry, referred to as uncoating, is critical yet poorly understood. Here we report a novel strategy to visualize HIV-1 uncoating using a fluorescently tagged oligo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913920/ https://www.ncbi.nlm.nih.gov/pubmed/27322072 http://dx.doi.org/10.1371/journal.ppat.1005709 |