Cargando…

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells

Disassembly of the cone-shaped HIV-1 capsid in target cells is a prerequisite for establishing a life-long infection. This step in HIV-1 entry, referred to as uncoating, is critical yet poorly understood. Here we report a novel strategy to visualize HIV-1 uncoating using a fluorescently tagged oligo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Francis, Ashwanth C., Marin, Mariana, Shi, Jiong, Aiken, Christopher, Melikyan, Gregory B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913920/ https://www.ncbi.nlm.nih.gov/pubmed/27322072 http://dx.doi.org/10.1371/journal.ppat.1005709

Ejemplares similares

HIV-1 Uncoating and Nuclear Import Precede the Completion of Reverse Transcription in Cell Lines and in Primary Macrophages
por: Francis, Ashwanth C., et al.
Publicado: (2020)

Live-Cell Imaging of Early Steps of Single HIV-1 Infection
por: Francis, Ashwanth C., et al.
Publicado: (2018)

Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles
por: Francis, Ashwanth C., et al.
Publicado: (2022)

Fluorescent protein-tagged Vpr dissociates from HIV-1 core after viral fusion and rapidly enters the cell nucleus
por: Desai, Tanay M., et al.
Publicado: (2015)

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay
por: Xu, Hongzhan, et al.
Publicado: (2013)

Revisiting HIV-1 uncoating
por: Arhel, Nathalie
Publicado: (2010)

Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization
por: Gres, Anna T., et al.
Publicado: (2023)

Strain and rupture of HIV-1 capsids during uncoating
por: Yu, Alvin, et al.
Publicado: (2022)

Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis
por: Márquez, Chantal L, et al.
Publicado: (2018)

Fluorescence Microscopy Assay to Measure HIV-1 Capsid Uncoating Kinetics in vitro
por: Márquez, Chantal L., et al.
Publicado: (2019)

Cytoplasmic Dynein Promotes HIV-1 Uncoating
por: Pawlica, Paulina, et al.
Publicado: (2014)

HIV-1 uncoats in the nucleus near sites of integration
por: Burdick, Ryan C., et al.
Publicado: (2020)

HIV-1 CA Inhibitors Are Antagonized by Inositol Phosphate Stabilization of the Viral Capsid in Cells
por: Sowd, Gregory A., et al.
Publicado: (2021)

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
por: Francis, Ashwanth C., et al.
Publicado: (2020)

Publisher Correction: HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
por: Francis, Ashwanth C., et al.
Publicado: (2020)

IP6 Regulation of HIV Capsid Assembly, Stability, and Uncoating
por: Dick, Robert A., et al.
Publicado: (2018)

Characterization of HIV-1 uncoating in human microglial cell lines
por: Ingram, Zachary, et al.
Publicado: (2020)

Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1
por: Hammonds, Jason E., et al.
Publicado: (2017)

HIV-1 capsid stability enables inositol phosphate-independent infection of target cells and promotes integration into genes
por: Sowd, Gregory A., et al.
Publicado: (2023)

Real-time dissection of dynamic uncoating of individual influenza viruses
por: Qin, Chong, et al.
Publicado: (2019)

Overlap Intensity: An ImageJ Macro for Analyzing the HIV-1 In Situ Uncoating Assay
por: Ingram, Zachary, et al.
Publicado: (2021)

A circular uncoating mechanism
por: Wells, William A.
Publicado: (2004)

Nuclear Import of the HIV-1 Core Precedes Reverse Transcription and Uncoating
por: Selyutina, Anastasia, et al.
Publicado: (2020)

Visualization of Content Release from Cell Surface-Attached Single HIV-1 Particles Carrying an Extra-Viral Fluorescent pH-Sensor
por: Sood, Chetan, et al.
Publicado: (2016)

MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1
por: Fricke, Thomas, et al.
Publicado: (2014)

Toward the “unravelling” of HIV: Host cell factors involved in HIV-1 core uncoating
por: Rawle, Daniel J., et al.
Publicado: (2018)

Potential role of heat shock protein 90 (Hsp90) in HIV uncoating
por: Joshi, Pheroze, et al.
Publicado: (2011)

Slower Uncoating Is Associated with Impaired Replicative Capability of Simian-Tropic HIV-1
por: Kono, Ken, et al.
Publicado: (2013)

HIV-1 uncoating in human CD4(+) T cells: kinetic and functional analyses
por: Chen, Nan-Yu, et al.
Publicado: (2013)

An HIV-1 capsid binding protein TRIM11 accelerates viral uncoating
por: Yuan, Ting, et al.
Publicado: (2016)

HIV-1 cores retain their integrity until minutes before uncoating in the nucleus
por: Li, Chenglei, et al.
Publicado: (2021)

Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid
por: Burse, Mallori, et al.
Publicado: (2017)

Role of nucleoporins in nuclear import and 3D location of HIV-1 in the nuclear compartment
por: Maeso, Ruben, et al.
Publicado: (2013)

Pinpointing retrovirus entry sites in cells expressing alternatively spliced receptor isoforms by single virus imaging
por: Padilla-Parra, Sergi, et al.
Publicado: (2014)

HIV-1 capsid uncoating initiates after the first strand transfer of reverse transcription
por: Cosnefroy, Ophélie, et al.
Publicado: (2016)

Daxx Inhibits HIV-1 Reverse Transcription and Uncoating in a SUMO-Dependent Manner
por: Maillet, Sarah, et al.
Publicado: (2020)

A simple, high-throughput stabilization assay to test HIV-1 uncoating inhibitors
por: Dostálková, Alžběta, et al.
Publicado: (2019)

Nuclear pore blockade reveals HIV-1 completes reverse transcription and uncoating in the nucleus
por: Dharan, Adarsh, et al.
Publicado: (2020)

Uncoated and coated blood contact surfaces of a hollow-fiber oxygenator: an in-vitro comparison
por: Baykut, D, et al.
Publicado: (1999)

Fluorescent Image Analysis of HIV-1 and HIV-2 Uncoating Kinetics in the Presence of Old World Monkey TRIM5α
por: Takeda, Eri, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hiioiunm8lkehsc90u35aon95q