A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks

Chromatin assembly factor 1 (CAF-1) is a histone H3–H4 chaperone that deposits newly synthesized histone (H3–H4)(2) tetramers during replication-coupled nucleosome assembly. However, how CAF-1 functions in this process is not yet well understood. Here, we report the crystal structure of C terminus o...

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Detalles Bibliográficos
Autores principales: Zhang, Kuo, Gao, Yuan, Li, Jingjing, Burgess, Rebecca, Han, Junhong, Liang, Huanhuan, Zhang, Zhiguo, Liu, Yingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914081/
https://www.ncbi.nlm.nih.gov/pubmed/26908650
http://dx.doi.org/10.1093/nar/gkw106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914081/
https://www.ncbi.nlm.nih.gov/pubmed/26908650
http://dx.doi.org/10.1093/nar/gkw106

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