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A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks
Chromatin assembly factor 1 (CAF-1) is a histone H3–H4 chaperone that deposits newly synthesized histone (H3–H4)(2) tetramers during replication-coupled nucleosome assembly. However, how CAF-1 functions in this process is not yet well understood. Here, we report the crystal structure of C terminus o...
Autores principales: | Zhang, Kuo, Gao, Yuan, Li, Jingjing, Burgess, Rebecca, Han, Junhong, Liang, Huanhuan, Zhang, Zhiguo, Liu, Yingfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914081/ https://www.ncbi.nlm.nih.gov/pubmed/26908650 http://dx.doi.org/10.1093/nar/gkw106 |
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