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A critical base pair in k-turns determines the conformational class adopted, and correlates with biological function

k-turns are commonly-occurring motifs that introduce sharp kinks into duplex RNA, thereby facilitating tertiary contacts. Both the folding and conformation of k-turns are determined by their local sequence. k-turns fall into two conformational classes, called N3 and N1, that differ in the pattern of...

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Detalles Bibliográficos
Autores principales: Huang, Lin, Wang, Jia, Lilley, David M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914095/
https://www.ncbi.nlm.nih.gov/pubmed/27016741
http://dx.doi.org/10.1093/nar/gkw201