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Staufen1 promotes HCV replication by inhibiting protein kinase R and transporting viral RNA to the site of translation and replication in the cells

Persistent hepatitis C virus (HCV) infection leads to chronic hepatitis C (CHC), which often progresses to liver cirrhosis (LC) and hepatocellular carcinoma (HCC). The molecular mechanisms that establish CHC and cause its subsequent development into LC and HCC are poorly understood. We have identifi...

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Detalles Bibliográficos
Autores principales: Dixit, Updesh, Pandey, Ashutosh K., Mishra, Priya, Sengupta, Amitabha, Pandey, Virendra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914112/
https://www.ncbi.nlm.nih.gov/pubmed/27106056
http://dx.doi.org/10.1093/nar/gkw312