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Stabilization of i-motif structures by 2′-β-fluorination of DNA

i-Motifs are four-stranded DNA structures consisting of two parallel DNA duplexes held together by hemi-protonated and intercalated cytosine base pairs (C:CH(+)). They have attracted considerable research interest for their potential role in gene regulation and their use as pH responsive switches an...

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Detalles Bibliográficos
Autores principales:	Assi, Hala Abou, Harkness, Robert W., Martin-Pintado, Nerea, Wilds, Christopher J., Campos-Olivas, Ramón, Mittermaier, Anthony K., González, Carlos, Damha, Masad J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914123/ https://www.ncbi.nlm.nih.gov/pubmed/27166371 http://dx.doi.org/10.1093/nar/gkw402

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