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SPATIAL: A System-level PAThway Impact AnaLysis approach
The goal of pathway analysis is to identify the pathways that are significantly impacted when a biological system is perturbed, e.g. by a disease or drug. Current methods treat pathways as independent entities. However, many signals are constantly sent from one pathway to another, essentially linkin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914126/ https://www.ncbi.nlm.nih.gov/pubmed/27193997 http://dx.doi.org/10.1093/nar/gkw429 |