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Structure-Specific nuclease activities of Artemis and the Artemis: DNA-PKcs complex
Artemis is a vertebrate nuclease with both endo- and exonuclease activities that acts on a wide range of nucleic acid substrates. It is the main nuclease in the non-homologous DNA end-joining pathway (NHEJ). Not only is Artemis important for the repair of DNA double-strand breaks (DSBs) in NHEJ, it...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914130/ https://www.ncbi.nlm.nih.gov/pubmed/27198222 http://dx.doi.org/10.1093/nar/gkw456 |