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Rapamycin-resistant and torin-sensitive mTOR signaling promotes the survival and proliferation of leukemic cells

The serine/threonine kinase mTOR is essential for the phosphoinositide 3-kinases (PI3K) signaling pathway, and regulates the development and function of immune cells. Aberrant activation of mTOR signaling pathway is associated with many cancers including leukemia. Here, we report the contributions o...

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Detalles Bibliográficos
Autores principales:	Park, Seohyun, Sim, Hyunsub, Lee, Keunwook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2016
Materias:	Research-Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914215/ https://www.ncbi.nlm.nih.gov/pubmed/26497580 http://dx.doi.org/10.5483/BMBRep.2016.49.1.201

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