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CCR5 deficiency accelerates lipopolysaccharide-induced astrogliosis, amyloid-beta deposit and impaired memory function
Chemokine receptors are implicated in inflammation and immune responses. Neuro-inflammation is associated with activation of astrocyte and amyloid-beta (Aβ) generations that lead to pathogenesis of Alzheimer disease (AD). Previous our study showed that deficiency of CC chemokine receptor 5 (CCR5) re...
Autores principales: | Hwang, Chul Ju, Park, Mi Hee, Hwang, Jae Yeon, Kim, Ju Hwan, Yun, Na Young, Oh, Sang Yeon, Song, Ju Kyung, Seo, Hyun Ok, Kim, Yun-Bae, Hwang, Dae Yeon, Oh, Ki-Wan, Han, Sang-Bae, Hong, Jin Tae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914263/ https://www.ncbi.nlm.nih.gov/pubmed/26910914 http://dx.doi.org/10.18632/oncotarget.7453 |
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