Cargando…

PGC-1α overexpression protects against aldosterone-induced podocyte depletion: role of mitochondria

Growing evidence has shown that podocyte number is a critical determinant for the development of glomerulosclerosis and progressive renal failure. We previously reported that mitochondrial dysfunction (MtD) is an early event in podocyte injury. Peroxisome proliferator-activated receptor-γ coactivato...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Min, Yuan, Yanggang, Bai, Mi, Ding, Guixia, Jia, Zhanjun, Huang, Songming, Zhang, Aihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914275/ https://www.ncbi.nlm.nih.gov/pubmed/26943584 http://dx.doi.org/10.18632/oncotarget.7859

Ejemplares similares

Huaier Cream Protects against Adriamycin-Induced Nephropathy by Restoring Mitochondrial Function via PGC-1α Upregulation
por: Che, Ruochen, et al.
Publicado: (2015)

Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-γ maintains the epithelial phenotype and antagonizes renal fibrogenesis
por: Zhao, Min, et al.
Publicado: (2016)

Inhibition of Mitochondrial Complex-1 Prevents the Downregulation of NKCC2 and ENaCα in Obstructive Kidney Disease
por: Zhang, Yue, et al.
Publicado: (2015)

miR-214 Protects Against Uric Acid-Induced Endothelial Cell Apoptosis
por: Yang, Bingyu, et al.
Publicado: (2020)

Overexpressed cyclophilin B suppresses aldosterone-induced proximal tubular cell injury both in vitro and in vivo
por: Wang, Bin, et al.
Publicado: (2016)

Expression of phospholipase A2 receptor in primary cultured podocytes derived from dog kidneys
por: SUGAHARA, Go, et al.
Publicado: (2016)

Role of COX-2/mPGES-1/Prostaglandin E2 Cascade in Kidney Injury
por: Jia, Zhanjun, et al.
Publicado: (2015)

Rotenone Remarkably Attenuates Oxidative Stress, Inflammation, and Fibrosis in Chronic Obstructive Uropathy
por: Sun, Ying, et al.
Publicado: (2014)

Mitochondria and PGC-1α in Aging and Age-Associated Diseases
por: Wenz, Tina
Publicado: (2011)

MnTBAP therapy attenuates the downregulation of sodium transporters in obstructive kidney disease
por: Liu, Mi, et al.
Publicado: (2017)

Mitochondrial aldehyde dehydrogenase obliterates insulin resistance-induced cardiac dysfunction through deacetylation of PGC-1α
por: Hu, Nan, et al.
Publicado: (2016)

Role of FOXO1 in aldosterone-induced autophagy: A compensatory protective mechanism related to podocyte injury
por: Wang, Bin, et al.
Publicado: (2016)

PGC-1α buffers ROS-mediated removal of mitochondria during myogenesis
por: Baldelli, S, et al.
Publicado: (2014)

Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α
por: Hatazawa, Yukino, et al.
Publicado: (2015)

Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-κB and improving mitochondrial function
por: Yu, Xiaowen, et al.
Publicado: (2018)

Overexpression of Her-2 in Biopsy-Proven Urothelial Carcinoma Patients From Pakistan
por: Chughtai, Anila, et al.
Publicado: (2022)

Constitutive PGC-1α overexpression in skeletal muscle does not protect from age-dependent decline in neurogenesis
por: Karlsson, Lars, et al.
Publicado: (2019)

The redox sensitive glycogen synthase kinase 3β suppresses the self-protective antioxidant response in podocytes upon oxidative glomerular injury
por: Li, Changbin, et al.
Publicado: (2015)

Whole‐genome sequencing revealed an interstitial deletion encompassing OCRL and SMARCA1 gene in a patient with Lowe syndrome
por: Zheng, Bixia, et al.
Publicado: (2019)

Toxicological assessment of multi-walled carbon nanotubes in vitro: potential mitochondria effects on male reproductive cells
por: Xu, Cheng, et al.
Publicado: (2016)

Hyperoside alleviates adriamycin-induced podocyte injury via inhibiting mitochondrial fission
por: Chen, Zhuyun, et al.
Publicado: (2017)

Podocyte Depletion in Thin GBM and Alport Syndrome
por: Wickman, Larysa, et al.
Publicado: (2016)

A rare case of pediatric recurrent rhabdomyolysis with compound heterogenous variants in the LPIN1
por: Che, Ruochen, et al.
Publicado: (2020)

A Potential Therapy Using Antisense Oligonucleotides to Treat Autosomal Recessive Polycystic Kidney Disease
por: Li, Huixia, et al.
Publicado: (2023)

Mechanisms and consequences of TGF-ß overexpression by podocytes in progressive podocyte disease
por: Lee, Hyun Soon
Publicado: (2011)

HIF-1α, HIF-2α, and ProExC: diagnostic or prognostic relevance in conjunctival intraepithelial neoplasia?
por: Nuessle, Simone, et al.
Publicado: (2020)

Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II-induced hypertension
por: Hong, Mo-Na, et al.
Publicado: (2016)

Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury
por: Ding, Wei, et al.
Publicado: (2016)

Podocyte Injury in Diabetic Kidney Disease: A Focus on Mitochondrial Dysfunction
por: Liu, Simeng, et al.
Publicado: (2022)

Fetal PGC-1α Overexpression Programs Adult Pancreatic β-Cell Dysfunction
por: Valtat, Bérengère, et al.
Publicado: (2013)

PGC1α overexpression preserves muscle mass and function in cisplatin‐induced cachexia
por: Huot, Joshua R., et al.
Publicado: (2022)

Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration
por: Washington, Tyrone A., et al.
Publicado: (2022)

Emerging Protective Actions of PGC-1α in Diabetic Nephropathy
por: She, Yuqing, et al.
Publicado: (2022)

Research Progress on Mechanism of Podocyte Depletion in Diabetic Nephropathy
por: Dai, Haoran, et al.
Publicado: (2017)

Altering the redox state of skeletal muscle by glutathione depletion increases the exercise‐activation of PGC‐1α
por: Strobel, Natalie A., et al.
Publicado: (2014)

Sodium wasting in potassium depletion: the role of aldosterone.
por: Catalona, W. J., et al.
Publicado: (1972)

Detection of α-defensin in eosinophils in helminth-infected mouse model
por: KHATUN, Afia, et al.
Publicado: (2018)

Splicing Characterization of CLCNKB Variants in Four Patients With Type III Bartter Syndrome
por: Wang, Chunli, et al.
Publicado: (2020)

Mycobacterial infection induces eosinophilia and production of α-defensin by eosinophils in mice
por: KHATUN, Afia, et al.
Publicado: (2018)

Podocyte Bioenergetics in the Development of Diabetic Nephropathy: The Role of Mitochondria
por: Audzeyenka, Irena, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i0l8e9ibit0a83h8mq5btj78f8