Cooperation of ETV6/RUNX1 and BCL2 enhances immunoglobulin production and accelerates glomerulonephritis in transgenic mice

The t(12;21) translocation generating the ETV6/RUNX1 fusion gene represents the most frequent chromosomal rearrangement in childhood leukemia. Presence of ETV6/RUNX1 alone is usually not sufficient for leukemia onset, and additional genetic alterations have to occur in ETV6/RUNX1-positive cells to c...

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Detalles Bibliográficos
Autores principales: Bauer, Eva, Schlederer, Michaela, Scheicher, Ruth, Horvath, Jaqueline, Aigner, Petra, Schiefer, Ana-Iris, Kain, Renate, Regele, Heinz, Hoermann, Gregor, Steiner, Günter, Kenner, Lukas, Sexl, Veronika, Villunger, Andreas, Moriggl, Richard, Stoiber, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914278/
https://www.ncbi.nlm.nih.gov/pubmed/26919255
http://dx.doi.org/10.18632/oncotarget.7687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914278/
https://www.ncbi.nlm.nih.gov/pubmed/26919255
http://dx.doi.org/10.18632/oncotarget.7687

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