Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma

Lung cancer is the leading cause of cancer death. Beyond first line treatment, few therapeutic options are available, particularly for squamous cell carcinoma (SCC). Here, we have explored the phospholipidomes of 30 human SCCs and found that they almost invariably (in 96.7% of cases) contain phospho...

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Detalles Bibliográficos
Autores principales: Marien, Eyra, Meister, Michael, Muley, Thomas, del Pulgar, Teresa Gomez, Derua, Rita, Spraggins, Jeffrey M., Van de Plas, Raf, Vanderhoydonc, Frank, Machiels, Jelle, Binda, Maria Mercedes, Dehairs, Jonas, Willette-Brown, Jami, Hu, Yinling, Dienemann, Hendrik, Thomas, Michael, Schnabel, Philipp A., Caprioli, Richard M., Lacal, Juan Carlos, Waelkens, Etienne, Swinnen, Johannes V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914306/
https://www.ncbi.nlm.nih.gov/pubmed/26862848
http://dx.doi.org/10.18632/oncotarget.7179

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