Induction of cancer testis antigen expression in circulating acute myeloid leukemia blasts following hypomethylating agent monotherapy

Cancer testis antigens (CTAs) are promising cancer associated antigens in solid tumors, but in acute myeloid leukemia, dense promoter methylation silences their expression. Leukemia cell lines exposed to HMAs induce expression of CTAs. We hypothesized that AML patients treated with standard of care...

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Detalles Bibliográficos
Autores principales: Srivastava, Pragya, Paluch, Benjamin E., Matsuzaki, Junko, James, Smitha R., Collamat-Lai, Golda, Blagitko-Dorfs, Nadja, Ford, Laurie Ann, Naqash, Rafeh, Lübbert, Michael, Karpf, Adam R., Nemeth, Michael J., Griffiths, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914325/
https://www.ncbi.nlm.nih.gov/pubmed/26883197
http://dx.doi.org/10.18632/oncotarget.7326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914325/
https://www.ncbi.nlm.nih.gov/pubmed/26883197
http://dx.doi.org/10.18632/oncotarget.7326

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