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MLN-8237: A dual inhibitor of aurora A and B in soft tissue sarcomas
Aurora kinases have become an attractive target in cancer therapy due to their deregulated expression in human tumors. Liposarcoma, a type of soft tissue sarcoma in adults, account for approximately 20% of all adult soft tissue sarcomas. There are no effective chemotherapies for majority of these tu...
Autores principales: | Nair, Jayasree S., Schwartz, Gary K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914329/ https://www.ncbi.nlm.nih.gov/pubmed/26887042 http://dx.doi.org/10.18632/oncotarget.7335 |
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