Cargando…
A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells
Signal Transducer and Activator of Transcription 3 (STAT3) is persistently activated in human liver and colon cancer cells and is required for cancer cell viability, survival and migration. Therefore, inhibition of STAT3 signaling may be a viable therapeutic approach for these two cancers. We recent...
Autores principales: | Zhao, Chongqiang, Wang, Wenlong, Yu, Wenying, Jou, David, Wang, Yina, Ma, Haiyan, Xiao, Hui, Qin, Hua, Zhang, Cuntai, Lü, Jiagao, Li, Sheng, Li, Chenglong, Lin, Jiayuh, Lin, Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914331/ https://www.ncbi.nlm.nih.gov/pubmed/26883202 http://dx.doi.org/10.18632/oncotarget.7338 |
Ejemplares similares
-
Growth-suppressive activity of raloxifene on liver cancer cells by targeting IL-6/GP130 signaling
por: Wang, Yina, et al.
Publicado: (2017) -
STAT3 as a potential therapeutic target in ALDH(+) and CD44(+)/CD24(+) stem cell-like pancreatic cancer cells
por: Lin, Li, et al.
Publicado: (2016) -
Alleviation of Inflammation and Oxidative Stress in Pressure Overload-Induced Cardiac Remodeling and Heart Failure via IL-6/STAT3 Inhibition by Raloxifene
por: Huo, Shengqi, et al.
Publicado: (2021) -
Bazedoxifene exhibits growth suppressive activity by targeting interleukin‐6/glycoprotein 130/signal transducer and activator of transcription 3 signaling in hepatocellular carcinoma
por: Ma, Haiyan, et al.
Publicado: (2019) -
Evaluation of STAT3 Signaling in ALDH+ and ALDH+/CD44+/CD24− Subpopulations of Breast Cancer Cells
por: Lin, Li, et al.
Publicado: (2013)