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MicroRNA-138 promotes acquired alkylator resistance in glioblastoma by targeting the Bcl-2-interacting mediator BIM
Glioblastoma is the most aggressive brain tumor in adults with a median survival below 12 months in population-based studies. The main reason for tumor recurrence and progression is constitutive or acquired resistance to the standard of care of surgical resection followed by radiotherapy with concom...
Autores principales: | Stojcheva, Nina, Schechtmann, Gennadi, Sass, Steffen, Roth, Patrick, Florea, Ana-Maria, Stefanski, Anja, Stühler, Kai, Wolter, Marietta, Müller, Nikola S., Theis, Fabian J., Weller, Michael, Reifenberger, Guido, Happold, Caroline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914333/ https://www.ncbi.nlm.nih.gov/pubmed/26887050 http://dx.doi.org/10.18632/oncotarget.7346 |
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