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Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme
A signaling molecule which is involved in proliferation and migration of malignant cells is the lipid mediator sphingosine-1-phosphate (S1P). There are hints for a potential role of S1P signaling in malignant brain tumors such as glioblastoma multiforme (GBM) which is characterized by a poor prognos...
Autores principales: | Bien-Möller, Sandra, Lange, Sandra, Holm, Tobias, Böhm, Andreas, Paland, Heiko, Küpper, Johannes, Herzog, Susann, Weitmann, Kerstin, Havemann, Christoph, Vogelgesang, Silke, Marx, Sascha, Hoffmann, Wolfgang, Schroeder, Henry W.S., Rauch, Bernhard H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914339/ https://www.ncbi.nlm.nih.gov/pubmed/26887055 http://dx.doi.org/10.18632/oncotarget.7366 |
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