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AEG-1/MTDH-activated autophagy enhances human malignant glioma susceptibility to TGF-β1-triggered epithelial-mesenchymal transition

Autophagy is a tightly regulated process activated in response to metabolic stress and other microenvironmental changes. Astrocyte elevated gene 1 (AEG-1) reportedly induces protective autophagy. Our results indicate that AEG-1 also enhances the susceptibility of malignant glioma cells to TGF-β1-tri...

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Detalles Bibliográficos
Autores principales: Zou, Meijuan, Zhu, Wei, Wang, Li, Shi, Lei, Gao, Rui, Ou, Yingwei, Chen, Xuguan, Wang, Zhongchang, Jiang, Aiqin, Liu, Kunmei, Xiao, Ming, Ni, Ping, Wu, Dandan, He, Wenping, Sun, Geng, Li, Ping, Zhai, Sulan, Wang, Xuerong, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914346/
https://www.ncbi.nlm.nih.gov/pubmed/26909607
http://dx.doi.org/10.18632/oncotarget.7536