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The autism associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain
The human MET gene imparts a replicated risk for autism spectrum disorder (ASD), and is implicated in the structural and functional integrity of brain. MET encodes a receptor tyrosine kinase, MET, which plays a pleiotropic role in embryogenesis and modifies a large number of neurodevelopmental event...
Autores principales: | Peng, Yun, Lu, Zhongming, Li, Guohui, Piechowicz, Mariel, Anderson, Miranda, Uddin, Yasin, Wu, Jie, Qiu, Shenfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914424/ https://www.ncbi.nlm.nih.gov/pubmed/26728565 http://dx.doi.org/10.1038/mp.2015.182 |
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