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YopN and TyeA Hydrophobic Contacts Required for Regulating Ysc-Yop Type III Secretion Activity by Yersinia pseudotuberculosis

Yersinia bacteria target Yop effector toxins to the interior of host immune cells by the Ysc-Yop type III secretion system. A YopN-TyeA heterodimer is central to controlling Ysc-Yop targeting activity. A + 1 frameshift event in the 3-prime end of yopN can also produce a singular secreted YopN-TyeA p...

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Detalles Bibliográficos
Autores principales: Amer, Ayad A. A., Gurung, Jyoti M., Costa, Tiago R. D., Ruuth, Kristina, Zavialov, Anton V., Forsberg, Åke, Francis, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914553/
https://www.ncbi.nlm.nih.gov/pubmed/27446813
http://dx.doi.org/10.3389/fcimb.2016.00066