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Pharmacological Targeting of the Hepcidin/Ferroportin Axis

The iron regulatory hormone hepcidin limits iron fluxes to the bloodstream by promoting degradation of the iron exporter ferroportin in target cells. Hepcidin insufficiency causes hyperabsorption of dietary iron, hyperferremia and tissue iron overload, which are hallmarks of hereditary hemochromatos...

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Detalles Bibliográficos
Autores principales:	Sebastiani, Giada, Wilkinson, Nicole, Pantopoulos, Kostas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914558/ https://www.ncbi.nlm.nih.gov/pubmed/27445804 http://dx.doi.org/10.3389/fphar.2016.00160

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