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Dynamic Changes in Local Protein Synthetic Machinery in Regenerating Central Nervous System Axons after Spinal Cord Injury
Intra-axonal localization of mRNAs and protein synthesis machinery (PSM) endows neurons with the capacity to generate proteins locally, allowing precise spatiotemporal regulation of the axonal response to extracellular stimuli. A number of studies suggest that this local translation is a promising t...
Autores principales: | Sachdeva, Rahul, Farrell, Kaitlin, McMullen, Mary-Katharine, Twiss, Jeffery L., Houle, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914735/ https://www.ncbi.nlm.nih.gov/pubmed/27375904 http://dx.doi.org/10.1155/2016/4087254 |
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