Cargando…

Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion

Erythroid cell commitment and differentiation proceed through activation of a lineage-restricted transcriptional network orchestrated by a group of well characterized genes. However, the minimal set of factors necessary for instructing red blood cell (RBC) development remains undefined. We employed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Capellera-Garcia, Sandra, Pulecio, Julian, Dhulipala, Kishori, Siva, Kavitha, Rayon-Estrada, Violeta, Singbrant, Sofie, Sommarin, Mikael N.E., Walkley, Carl R., Soneji, Shamit, Karlsson, Göran, Raya, Ángel, Sankaran, Vijay G., Flygare, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914771/ https://www.ncbi.nlm.nih.gov/pubmed/27264182 http://dx.doi.org/10.1016/j.celrep.2016.05.027

Ejemplares similares

Single-cell multiomics of human fetal hematopoiesis define a developmental-specific population and a fetal signature
por: Sommarin, Mikael N. E., et al.
Publicado: (2023)

Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis
por: Jensen, Christina T., et al.
Publicado: (2018)

Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond–Blackfan anaemia
por: Sjögren, Sara E., et al.
Publicado: (2015)

Prospective isolation of radiation induced erythroid stress progenitors reveals unique transcriptomic and epigenetic signatures enabling increased erythroid output
por: Singbrant, Sofie, et al.
Publicado: (2020)

Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity
por: Mattebo, Alexander, et al.
Publicado: (2021)

Gene expression profiling to define the cell intrinsic role of the SKI proto-oncogene in hematopoiesis and myeloid neoplasms
por: Chalk, Alistair M., et al.
Publicado: (2014)

Defining the Emerging Blood System During Development at Single-Cell Resolution
por: Karlsson, Göran, et al.
Publicado: (2021)

SCExV: a webtool for the analysis and visualisation of single cell qRT-PCR data
por: Lang, Stefan, et al.
Publicado: (2015)

Zfp36l2 is required for self-renewal of early erythroid BFU-E progenitors
por: Zhang, Lingbo, et al.
Publicado: (2013)

Scarf enables a highly memory-efficient analysis of large-scale single-cell genomics data
por: Dhapola, Parashar, et al.
Publicado: (2022)

Smad4 is critical for self-renewal of hematopoietic stem cells
por: Karlsson, Göran, et al.
Publicado: (2007)

Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells
por: Warsi, Sarah, et al.
Publicado: (2022)

Bioinformatics and the Metaverse: Are We Ready?
por: Taylor, Stephen, et al.
Publicado: (2022)

Molecular and cellular mechanisms that regulate human erythropoiesis
por: Caulier, Alexis L., et al.
Publicado: (2022)

Update on the Pathogenic Implications and Clinical Potential of microRNAs in Cardiac Disease
por: Notari, Mario, et al.
Publicado: (2015)

B-lineage acute lymphoblastic leukemia causes cell-autonomous defects in long-term hematopoietic stem cell function
por: Jensen, Christina T., et al.
Publicado: (2023)

Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence
por: Oburoglu, Leal, et al.
Publicado: (2021)

Decreased PGC1β expression results in disrupted human erythroid differentiation, impaired hemoglobinization and cell cycle exit
por: Sen, Taha, et al.
Publicado: (2021)

The Role of α(1)-Microglobulin (A1M) in Erythropoiesis and Erythrocyte Homeostasis—Therapeutic Opportunities in Hemolytic Conditions
por: Kristiansson, Amanda, et al.
Publicado: (2020)

Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors
por: May, Gillian, et al.
Publicado: (2013)

Networking erythropoiesis
por: Kerenyi, Marc A., et al.
Publicado: (2010)

Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis
por: Ludwig, Leif S., et al.
Publicado: (2019)

HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis
por: Zhang, Shuping, et al.
Publicado: (2019)

Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging
por: Säwen, Petter, et al.
Publicado: (2018)

Bone Matrix Proteins: Isolation and Characterization of a Novel Cell-binding Keratan Sulfate Proteoglycan (Osteoadherin) from Bovine Bone
por: Wendel, Mikael, et al.
Publicado: (1998)

Scalp fibroblasts have a shared expression profile in monogenic craniosynostosis
por: Bochukova, Elena G, et al.
Publicado: (2009)

Small molecules increase direct neural conversion of human fibroblasts
por: Pfisterer, Ulrich, et al.
Publicado: (2016)

Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias
por: Rundberg Nilsson, Alexandra, et al.
Publicado: (2016)

CellexalVR: A virtual reality platform to visualize and analyze single-cell omics data
por: Legetth, Oscar, et al.
Publicado: (2021)

Erythropoietin and the Regulation of Erythropoiesis
por: Mc Phedran, Peter
Publicado: (1971)

In Vitro Aspects of Erythropoiesis
por: Lord, B. I.
Publicado: (1980)

Phylogeny and Ontogeny of Erythropoiesis
por: Nunomura, Wataru, et al.
Publicado: (2015)

Transferrin Receptors in Erythropoiesis
por: Richard, Cyrielle, et al.
Publicado: (2020)

Iron Mining for Erythropoiesis
por: Correnti, Margherita, et al.
Publicado: (2022)

Editorial: Stress erythropoiesis
por: de Vasconcellos, Jaira Ferreira, et al.
Publicado: (2023)

Nitric Oxide-cGMP Signaling Stimulates Erythropoiesis through Multiple Lineage-Specific Transcription Factors: Clinical Implications and a Novel Target for Erythropoiesis
por: Ikuta, Tohru, et al.
Publicado: (2016)

Single-Cell Network Analysis Identifies DDIT3 as a Nodal Lineage Regulator in Hematopoiesis
por: Pina, Cristina, et al.
Publicado: (2015)

Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis
por: Säwén, Petter, et al.
Publicado: (2016)

Human Primary Bone Marrow Mesenchymal Stromal Cells and Their in vitro Progenies Display Distinct Transcriptional Profile Signatures
por: Ghazanfari, Roshanak, et al.
Publicado: (2017)

Hif-1α Deletion May Lead to Adverse Treatment Effect in a Mouse Model of MLL-AF9-Driven AML
por: Velasco-Hernandez, Talia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dmb94vmts7q4ignh2lsvjesaj2