Cargando…
High salt promotes autoimmunity by TET2-induced DNA demethylation and driving the differentiation of Tfh cells
Follicular helper T cells (Tfh) have been well documented to play a critical role in autoimmunity, such as systemic lupus erythematosus (SLE), by helping B cells. In this study, high salt (sodium chloride, NaCl), under physiological conditions, was demonstrated to increase the differentiation of Tfh...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914849/ https://www.ncbi.nlm.nih.gov/pubmed/27325182 http://dx.doi.org/10.1038/srep28065 |