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Transformed MDCK cells secrete elevated MMP1 that generates LAMA5 fragments promoting endothelial cell angiogenesis

Epithelial-mesenchymal transition (EMT) enhances the migration and invasion of cancer cells, and is regulated by various molecular mechanisms including extracellular matrix metalloproteinase (MMP) activity. Previously, we reported transformation of epithelial Madin-Darby canine kidney (MDCK) cells w...

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Detalles Bibliográficos
Autores principales:	Gopal, Shashi K., Greening, David W., Zhu, Hong-Jian, Simpson, Richard J., Mathias, Rommel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914959/ https://www.ncbi.nlm.nih.gov/pubmed/27324842 http://dx.doi.org/10.1038/srep28321

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