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Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A(2A) receptors

Synaptic plasticity in the autoassociative network of recurrent connections among hippocampal CA3 pyramidal cells is thought to enable the storage of episodic memory. Impaired episodic memory is an early manifestation of cognitive deficits in Alzheimer's disease (AD). In the APP/PS1 mouse model...

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Detalles Bibliográficos
Autores principales:	Viana da Silva, Silvia, Haberl, Matthias Georg, Zhang, Pei, Bethge, Philipp, Lemos, Cristina, Gonçalves, Nélio, Gorlewicz, Adam, Malezieux, Meryl, Gonçalves, Francisco Q., Grosjean, Noëlle, Blanchet, Christophe, Frick, Andreas, Nägerl, U Valentin, Cunha, Rodrigo A., Mulle, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915032/ https://www.ncbi.nlm.nih.gov/pubmed/27312972 http://dx.doi.org/10.1038/ncomms11915

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