Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology

Diagnosis of acute lung allograft rejection is currently based on transbronchial lung biopsies. Additional methods to detect acute allograft dysfunction derived from plasma and bronchoalveolar lavage samples might facilitate diagnosis and ultimately improve allograft survival. This review article gi...

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Autores principales: Speck, Nicole E., Schuurmans, Macé M., Murer, Christian, Benden, Christian, Huber, Lars C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915079/
https://www.ncbi.nlm.nih.gov/pubmed/27323950
http://dx.doi.org/10.1186/s12931-016-0391-y
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author Speck, Nicole E.
Schuurmans, Macé M.
Murer, Christian
Benden, Christian
Huber, Lars C.
author_facet Speck, Nicole E.
Schuurmans, Macé M.
Murer, Christian
Benden, Christian
Huber, Lars C.
author_sort Speck, Nicole E.
collection PubMed
description Diagnosis of acute lung allograft rejection is currently based on transbronchial lung biopsies. Additional methods to detect acute allograft dysfunction derived from plasma and bronchoalveolar lavage samples might facilitate diagnosis and ultimately improve allograft survival. This review article gives an overview of the cell profiles of bronchoalveolar lavage and plasma samples during acute lung allograft rejection. The value of these cells and changes within the pattern of differential cytology to support the diagnosis of acute lung allograft rejection is discussed. Current findings on the topic are highlighted and trends for future research are identified.
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spelling pubmed-49150792016-06-22 Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology Speck, Nicole E. Schuurmans, Macé M. Murer, Christian Benden, Christian Huber, Lars C. Respir Res Review Diagnosis of acute lung allograft rejection is currently based on transbronchial lung biopsies. Additional methods to detect acute allograft dysfunction derived from plasma and bronchoalveolar lavage samples might facilitate diagnosis and ultimately improve allograft survival. This review article gives an overview of the cell profiles of bronchoalveolar lavage and plasma samples during acute lung allograft rejection. The value of these cells and changes within the pattern of differential cytology to support the diagnosis of acute lung allograft rejection is discussed. Current findings on the topic are highlighted and trends for future research are identified. BioMed Central 2016-06-21 2016 /pmc/articles/PMC4915079/ /pubmed/27323950 http://dx.doi.org/10.1186/s12931-016-0391-y Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Speck, Nicole E.
Schuurmans, Macé M.
Murer, Christian
Benden, Christian
Huber, Lars C.
Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology
title Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology
title_full Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology
title_fullStr Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology
title_full_unstemmed Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology
title_short Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology
title_sort diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915079/
https://www.ncbi.nlm.nih.gov/pubmed/27323950
http://dx.doi.org/10.1186/s12931-016-0391-y
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