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AMD and the alternative complement pathway: genetics and functional implications

Age-related macular degeneration (AMD) is an ocular neurodegenerative disorder and is the leading cause of legal blindness in Western societies, with a prevalence of up to 8 % over the age of 60, which continues to increase with age. AMD is characterized by the progressive breakdown of the macula (t...

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Detalles Bibliográficos
Autores principales:	Tan, Perciliz L., Bowes Rickman, Catherine, Katsanis, Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915094/ https://www.ncbi.nlm.nih.gov/pubmed/27329102 http://dx.doi.org/10.1186/s40246-016-0079-x

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