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Advanced abdominal imaging with dual energy CT is feasible without increasing radiation dose

BACKGROUND: Dual energy CT (DECT) has proven its potential in oncological imaging. Considering the repeated follow-up examinations, radiation dose should not exceed conventional single energy CT (SECT). Comparison studies on the same scanner with a large number of patients, considering patient geome...

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Autores principales: Uhrig, Monika, Simons, David, Kachelrieß, Marc, Pisana, Francesco, Kuchenbecker, Stefan, Schlemmer, Heinz-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915171/
https://www.ncbi.nlm.nih.gov/pubmed/27329159
http://dx.doi.org/10.1186/s40644-016-0073-5
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author Uhrig, Monika
Simons, David
Kachelrieß, Marc
Pisana, Francesco
Kuchenbecker, Stefan
Schlemmer, Heinz-Peter
author_facet Uhrig, Monika
Simons, David
Kachelrieß, Marc
Pisana, Francesco
Kuchenbecker, Stefan
Schlemmer, Heinz-Peter
author_sort Uhrig, Monika
collection PubMed
description BACKGROUND: Dual energy CT (DECT) has proven its potential in oncological imaging. Considering the repeated follow-up examinations, radiation dose should not exceed conventional single energy CT (SECT). Comparison studies on the same scanner with a large number of patients, considering patient geometries and image quality, and exploiting full potential of SECT dose reduction are rare. Purpose of this retrospective study was to compare dose of dual source DECT versus dose-optimized SECT abdominal imaging in clinical routine. METHODS: One hundred patients (62y (±14)) had either contrast-enhanced SECT including automatic voltage control (44) or DECT (56). CT dose index (CTDIvol), size-specific dose-estimate (SSDE) and dose-length product (DLP) were reported. Image noise (SD) was recorded as mean of three ROIs placed in subcutaneous fat and normalized to dose by [Formula: see text] . For dose-normalized contrast-to-noise ratio (CNRD), mean attenuation of psoas muscle (CT(muscle)) and subcutaneous fat (CT(fat)) were compared by CNRD = (CTmuscle − CTfat)/SDn. Statistical significance was tested with two-sided t-test (α = 0.05). RESULTS: There was no significant difference (p < 0.05) between DECT and SECT: Mean CTDIvol was 14.2 mGy (±3.9) (DECT) and 14.3 mGy (±4.5) (SECT). Mean DLP was 680 mGy*cm (±220) (DECT) and 665 mGy*cm (±231) (SECT). Mean SSDE was 15.7 mGy (±1.9) (DECT) and 16.1 mGy (±2.5) (SECT). Mean SDn was 42.2 (±13.9) HU [Formula: see text] (DECT) and 47.8 (±14.9) HU [Formula: see text] (SECT). Mean CNRD was 3.9 (±1.3) [Formula: see text] . (DECT) and 4.0 (±1.3) [Formula: see text] (SECT). CONCLUSION: Abdominal DECT is feasible without increasing radiation dose or deteriorating image quality, even compared to dose-optimized SECT including automatic voltage control. Thus DECT can contribute to sophisticated oncological imaging without dose penalty.
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spelling pubmed-49151712016-06-22 Advanced abdominal imaging with dual energy CT is feasible without increasing radiation dose Uhrig, Monika Simons, David Kachelrieß, Marc Pisana, Francesco Kuchenbecker, Stefan Schlemmer, Heinz-Peter Cancer Imaging Research Article BACKGROUND: Dual energy CT (DECT) has proven its potential in oncological imaging. Considering the repeated follow-up examinations, radiation dose should not exceed conventional single energy CT (SECT). Comparison studies on the same scanner with a large number of patients, considering patient geometries and image quality, and exploiting full potential of SECT dose reduction are rare. Purpose of this retrospective study was to compare dose of dual source DECT versus dose-optimized SECT abdominal imaging in clinical routine. METHODS: One hundred patients (62y (±14)) had either contrast-enhanced SECT including automatic voltage control (44) or DECT (56). CT dose index (CTDIvol), size-specific dose-estimate (SSDE) and dose-length product (DLP) were reported. Image noise (SD) was recorded as mean of three ROIs placed in subcutaneous fat and normalized to dose by [Formula: see text] . For dose-normalized contrast-to-noise ratio (CNRD), mean attenuation of psoas muscle (CT(muscle)) and subcutaneous fat (CT(fat)) were compared by CNRD = (CTmuscle − CTfat)/SDn. Statistical significance was tested with two-sided t-test (α = 0.05). RESULTS: There was no significant difference (p < 0.05) between DECT and SECT: Mean CTDIvol was 14.2 mGy (±3.9) (DECT) and 14.3 mGy (±4.5) (SECT). Mean DLP was 680 mGy*cm (±220) (DECT) and 665 mGy*cm (±231) (SECT). Mean SSDE was 15.7 mGy (±1.9) (DECT) and 16.1 mGy (±2.5) (SECT). Mean SDn was 42.2 (±13.9) HU [Formula: see text] (DECT) and 47.8 (±14.9) HU [Formula: see text] (SECT). Mean CNRD was 3.9 (±1.3) [Formula: see text] . (DECT) and 4.0 (±1.3) [Formula: see text] (SECT). CONCLUSION: Abdominal DECT is feasible without increasing radiation dose or deteriorating image quality, even compared to dose-optimized SECT including automatic voltage control. Thus DECT can contribute to sophisticated oncological imaging without dose penalty. BioMed Central 2016-06-21 /pmc/articles/PMC4915171/ /pubmed/27329159 http://dx.doi.org/10.1186/s40644-016-0073-5 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Uhrig, Monika
Simons, David
Kachelrieß, Marc
Pisana, Francesco
Kuchenbecker, Stefan
Schlemmer, Heinz-Peter
Advanced abdominal imaging with dual energy CT is feasible without increasing radiation dose
title Advanced abdominal imaging with dual energy CT is feasible without increasing radiation dose
title_full Advanced abdominal imaging with dual energy CT is feasible without increasing radiation dose
title_fullStr Advanced abdominal imaging with dual energy CT is feasible without increasing radiation dose
title_full_unstemmed Advanced abdominal imaging with dual energy CT is feasible without increasing radiation dose
title_short Advanced abdominal imaging with dual energy CT is feasible without increasing radiation dose
title_sort advanced abdominal imaging with dual energy ct is feasible without increasing radiation dose
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915171/
https://www.ncbi.nlm.nih.gov/pubmed/27329159
http://dx.doi.org/10.1186/s40644-016-0073-5
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