Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration

BACKGROUND: Human antigen R (HuR) is an RNA binding protein that is overexpressed in many human cancers, including lung cancer, and has been shown to regulate the expression of several oncoproteins. Further, HuR overexpression in cancer cells has been associated with poor-prognosis and therapy resis...

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Detalles Bibliográficos
Autores principales: Muralidharan, Ranganayaki, Babu, Anish, Amreddy, Narsireddy, Basalingappa, Kanthesh, Mehta, Meghna, Chen, Allshine, Zhao, Yan Daniel, Kompella, Uday B., Munshi, Anupama, Ramesh, Rajagopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915183/
https://www.ncbi.nlm.nih.gov/pubmed/27328938
http://dx.doi.org/10.1186/s12951-016-0201-1

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