Plasma membrane repairs by small GTPase Rab3a

Lysosomes fuse with the plasma membrane to help repair membrane lesions, but how they are positioned close to these lesions is not fully understood. Now, Encarnação et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201511093) demonstrate that the lysosomal GTPase Rab3a and its effectors orch...

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Detalles Bibliográficos
Autores principales: Raiborg, Camilla, Stenmark, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915196/
https://www.ncbi.nlm.nih.gov/pubmed/27325788
http://dx.doi.org/10.1083/jcb.201606006
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author Raiborg, Camilla
Stenmark, Harald
author_facet Raiborg, Camilla
Stenmark, Harald
author_sort Raiborg, Camilla
collection PubMed
description Lysosomes fuse with the plasma membrane to help repair membrane lesions, but how they are positioned close to these lesions is not fully understood. Now, Encarnação et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201511093) demonstrate that the lysosomal GTPase Rab3a and its effectors orchestrate lysosome positioning and plasma membrane repair.
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spelling pubmed-49151962016-12-20 Plasma membrane repairs by small GTPase Rab3a Raiborg, Camilla Stenmark, Harald J Cell Biol Commentary Lysosomes fuse with the plasma membrane to help repair membrane lesions, but how they are positioned close to these lesions is not fully understood. Now, Encarnação et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201511093) demonstrate that the lysosomal GTPase Rab3a and its effectors orchestrate lysosome positioning and plasma membrane repair. The Rockefeller University Press 2016-06-20 /pmc/articles/PMC4915196/ /pubmed/27325788 http://dx.doi.org/10.1083/jcb.201606006 Text en © 2016 Raiborg and Stenmark This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Raiborg, Camilla
Stenmark, Harald
Plasma membrane repairs by small GTPase Rab3a
title Plasma membrane repairs by small GTPase Rab3a
title_full Plasma membrane repairs by small GTPase Rab3a
title_fullStr Plasma membrane repairs by small GTPase Rab3a
title_full_unstemmed Plasma membrane repairs by small GTPase Rab3a
title_short Plasma membrane repairs by small GTPase Rab3a
title_sort plasma membrane repairs by small gtpase rab3a
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915196/
https://www.ncbi.nlm.nih.gov/pubmed/27325788
http://dx.doi.org/10.1083/jcb.201606006
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