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Crotamine stimulates phagocytic activity by inducing nitric oxide and TNF-α via p38 and NFκ-B signaling in RAW 264.7 macrophages
Crotamine is a peptide toxin found in the venom of the rattlesnake Crotalus durissus terrificus and has antiproliferative, antimicrobial, and antifungal activities. Herein, we show that crotamine dose-dependently induced macrophage phagocytic and cytostatic activity by the induction of nitric oxide...
Autores principales: | Lee, Kyung Jin, Kim, Yun Kyu, Krupa, Martin, Nguyen, Anh Ngoc, Do, Bich Hang, Chung, Boram, Vu, Thi Thu Trang, Kim, Song Cheol, Choe, Han |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915234/ https://www.ncbi.nlm.nih.gov/pubmed/26818089 http://dx.doi.org/10.5483/BMBRep.2016.49.3.271 |
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